Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/29/21 1:30 PM | 11/29/21 1:30 PM | Ternana Calcio | FC Crotone | 1-0 | 5 - 7 points |
| 11/30/21 11:00 AM | 11/30/21 11:00 AM | US Cremonese | Frosinone Calcio | 1-1 | 5 - 7 points |
| 11/30/21 11:00 AM | 11/30/21 11:00 AM | Pisa Sporting Club | AC Perugia | 1-1 | 5 - 7 points |
| 11/30/21 1:30 PM | 11/30/21 1:30 PM | AC Monza | Cosenza Calcio | 4-1 | 5 - 7 points |
| 11/30/21 1:30 PM | 11/30/21 1:30 PM | Vicenza Calcio | Benevento Calcio | 2-3 | 5 - 7 points |
| 11/30/21 1:30 PM | 11/30/21 1:30 PM | Reggina 1914 | Ascoli Calcio | 1-2 | 5 - 7 points |
| 11/30/21 1:30 PM | 11/30/21 1:30 PM | SPAL Ferrara | US Lecce | 1-3 | 5 - 7 points |
| 11/30/21 1:30 PM | 11/30/21 1:30 PM | Pordenone | Alessandria Calcio | 2-0 | 5 - 7 points |
| 12/1/21 11:00 AM | 12/1/21 11:00 AM | Parma Calcio 1913 | Brescia Calcio | 0-1 | 5 - 7 points |
| 12/1/21 1:30 PM | 12/1/21 1:30 PM | AS Cittadella | Como Calcio | 2-2 | 5 - 7 points |