Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/20/21 7:00 AM | 11/20/21 7:00 AM | Ternana Calcio | AS Cittadella | 1-1 | 5 - 7 points |
| 11/20/21 7:00 AM | 11/20/21 7:00 AM | Pordenone | Ascoli Calcio | 0-1 | 5 - 7 points |
| 11/20/21 7:00 AM | 11/20/21 7:00 AM | Frosinone Calcio | US Lecce | 0-0 | 5 - 7 points |
| 11/20/21 7:00 AM | 11/20/21 7:00 AM | SPAL Ferrara | Alessandria Calcio | 2-3 | 5 - 7 points |
| 11/20/21 9:15 AM | 11/20/21 9:15 AM | AC Perugia | FC Crotone | 2-0 | 5 - 7 points |
| 11/20/21 11:30 AM | 11/20/21 11:30 AM | Vicenza Calcio | Brescia Calcio | 2-3 | 5 - 7 points |
| 11/21/21 7:00 AM | 11/21/21 7:00 AM | Parma Calcio 1913 | Cosenza Calcio | 1-1 | 5 - 7 points |
| 11/21/21 7:00 AM | 11/21/21 7:00 AM | Reggina 1914 | US Cremonese | 1-2 | 5 - 7 points |
| 11/21/21 9:15 AM | 11/21/21 9:15 AM | AC Monza | Como Calcio | 3-2 | 5 - 7 points |
| 11/21/21 1:30 PM | 11/21/21 1:30 PM | Pisa Sporting Club | Benevento Calcio | 1-0 | 5 - 7 points |