Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | Stade Toulousain | Biarritz | 80-7 | 3 - 10 - 10 |
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | USA Perpignan | Union Bordeaux Bègles | 22-15 | 7 - 10 - 3 |
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | ASM Clermont Auvergne | Montpellier Hérault RC | 20-15 | 3 - 10 - 6 |
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | Stade Français | CA Brive | 17-33 | 3 - 10 - 10 |
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | Lyon OU | Atlantique Stade Rochelais | 26-29 | 4 - 10 - 5 |
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | Racing Métro 92 | RC Toulon | 21-16 | 4 - 10 - 5 |
| 6/5/22 2:05 PM | 6/5/22 2:05 PM | Section Paloise | Castres Olympique | 16-26 | 5 - 10 - 4 |