Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 5/21/22 8:00 AM | 5/21/22 8:00 AM | Union Bordeaux Bègles | Lyon OU | 42-10 | 3 - 10 - 10 |
| 5/21/22 10:15 AM | 5/21/22 10:15 AM | Biarritz | ASM Clermont Auvergne | 8-26 | 10 - 10 - 3 |
| 5/21/22 10:15 AM | 5/21/22 10:15 AM | RC Toulon | Section Paloise | 37-20 | 3 - 10 - 10 |
| 5/21/22 10:15 AM | 5/21/22 10:15 AM | Atlantique Stade Rochelais | Stade Français | 32-13 | 3 - 10 - 10 |
| 5/21/22 10:15 AM | 5/21/22 10:15 AM | Montpellier Hérault RC | Racing Métro 92 | 22-13 | 3 - 10 - 10 |
| 5/21/22 2:05 PM | 5/21/22 2:05 PM | CA Brive | Stade Toulousain | 8-26 | 9 - 10 - 3 |
| 5/22/22 2:05 PM | 5/22/22 2:05 PM | Castres Olympique | USA Perpignan | 28-12 | 3 - 10 - 10 |