Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/26/22 9:00 AM | 3/26/22 9:00 AM | RC Toulon | ASM Clermont Auvergne | 32-22 | 3 - 10 - 6 |
| 3/26/22 11:00 AM | 3/26/22 11:00 AM | Atlantique Stade Rochelais | Racing Métro 92 | 19-0 | 3 - 10 - 9 |
| 3/26/22 11:00 AM | 3/26/22 11:00 AM | Section Paloise | USA Perpignan | 27-22 | 3 - 10 - 10 |
| 3/26/22 11:00 AM | 3/26/22 11:00 AM | Montpellier Hérault RC | Biarritz | 37-22 | 3 - 10 - 10 |
| 3/26/22 11:00 AM | 3/26/22 11:00 AM | CA Brive | Castres Olympique | 28-12 | 4 - 10 - 4 |
| 3/26/22 3:05 PM | 3/26/22 3:05 PM | Stade Français | Union Bordeaux Bègles | 18-31 | 3 - 10 - 6 |
| 3/27/22 2:05 PM | 3/27/22 2:05 PM | Stade Toulousain | Lyon OU | 27-19 | 3 - 10 - 10 |