Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/11/21 8:00 AM | 9/11/21 8:00 AM | Section Paloise | Lyon OU | 21-17 | 5 - 10 - 4 |
| 9/11/21 8:00 AM | 9/11/21 8:00 AM | ASM Clermont Auvergne | Castres Olympique | 30-34 | 3 - 10 - 10 |
| 9/11/21 8:05 AM | 9/11/21 8:05 AM | USA Perpignan | Biarritz | 33-20 | 4 - 10 - 5 |
| 9/11/21 8:05 AM | 9/11/21 8:05 AM | Montpellier Hérault RC | CA Brive | 39-17 | 3 - 10 - 10 |
| 9/11/21 10:15 AM | 9/11/21 10:15 AM | Union Bordeaux Bègles | Stade Français | 37-10 | 3 - 10 - 8 |
| 9/11/21 2:05 PM | 9/11/21 2:05 PM | Racing Métro 92 | Atlantique Stade Rochelais | 23-10 | 3 - 10 - 7 |
| 9/12/21 2:05 PM | 9/12/21 2:05 PM | Stade Toulousain | RC Toulon | 41-10 | 3 - 10 - 10 |