Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/14/22 1:45 PM | 10/14/22 1:45 PM | KVC Westerlo | RFC Seraing | 2-2 | 5 - 7 points |
| 10/15/22 9:00 AM | 10/15/22 9:00 AM | KV Kortrijk | SV Zulte-Waregem | 1-3 | 5 - 7 points |
| 10/15/22 11:15 AM | 10/15/22 11:15 AM | KSV Cercle Brügge | KAS Eupen | 5-1 | 5 - 7 points |
| 10/15/22 11:15 AM | 10/15/22 11:15 AM | Sint-Truidense VV | Sporting Charleroi | 2-1 | 5 - 7 points |
| 10/15/22 1:45 PM | 10/15/22 1:45 PM | OH Leuven | KRC Genk | 0-1 | 5 - 7 points |
| 10/16/22 6:30 AM | 10/16/22 6:30 AM | Standard Liège | Royal Antwerp FC | 3-0 | 5 - 7 points |
| 10/16/22 9:00 AM | 10/16/22 9:00 AM | KAA Gent | KV Mechelen | 3-0 | 5 - 7 points |
| 10/16/22 11:30 AM | 10/16/22 11:30 AM | RSC Anderlecht | Club Brugge | 0-1 | 5 - 7 points |
| 10/16/22 2:00 PM | 10/16/22 2:00 PM | KV Oostende | Royale Union Saint-Gilloise | 1-6 | 5 - 7 points |