| Date | Home | Away | Result |
|---|---|---|---|
| 8/15/25 1:45 PM | OH Leuven | KRC Genk | 1-2 |
| 8/16/25 9:00 AM | SV Zulte-Waregem | Club Brugge | 0-1 |
| 8/16/25 11:15 AM | KV Mechelen | KAA Gent | 1-1 |
| 8/16/25 1:45 PM | Royale Union Saint-Gilloise | Standard Liège | 3-0 |
| 8/17/25 6:30 AM | FCV Dender EH | RSC Anderlecht | 0-2 |
| 8/17/25 9:00 AM | Sint-Truidense VV | RAAL La Louviere | 2-1 |
| 8/17/25 11:30 AM | Sporting Charleroi | Royal Antwerp FC | 1-1 |
| 8/17/25 12:15 PM | KSV Cercle Brügge | KVC Westerlo | 4-1 |