| Date | Home | Away | Result |
|---|---|---|---|
| 4/14/23 1:45 PM | Standard Liège | Sporting Charleroi | 3-1 |
| 4/15/23 9:00 AM | KAS Eupen | SV Zulte-Waregem | 1-5 |
| 4/15/23 11:15 AM | KV Oostende | OH Leuven | 0-4 |
| 4/15/23 11:15 AM | KSV Cercle Brügge | Sint-Truidense VV | 3-1 |
| 4/15/23 1:45 PM | KVC Westerlo | Club Brugge | 0-0 |
| 4/16/23 6:30 AM | KRC Genk | RSC Anderlecht | 5-2 |
| 4/16/23 9:00 AM | KV Mechelen | KAA Gent | 1-1 |
| 4/16/23 11:30 AM | Royal Antwerp FC | KV Kortrijk | 1-0 |
| 4/16/23 12:15 PM | Royale Union Saint-Gilloise | RFC Seraing | 2-1 |