| Date | Home | Away | Result |
|---|---|---|---|
| 8/8/25 1:45 PM | Sint-Truidense VV | FCV Dender EH | 2-0 |
| 8/9/25 9:00 AM | Club Brugge | KSV Cercle Brügge | 2-0 |
| 8/9/25 11:15 AM | KVC Westerlo | KV Mechelen | 0-1 |
| 8/9/25 1:45 PM | KAA Gent | Royale Union Saint-Gilloise | 2-3 |
| 8/10/25 6:30 AM | RAAL La Louviere | Sporting Charleroi | 1-0 |
| 8/10/25 9:00 AM | RSC Anderlecht | SV Zulte-Waregem | 2-3 |
| 8/10/25 11:30 AM | Standard Liège | KRC Genk | 2-1 |
| 8/10/25 12:15 PM | Royal Antwerp FC | OH Leuven | 3-1 |