| Date | Home | Away | Result |
|---|---|---|---|
| 2/3/23 1:45 PM | KV Oostende | RSC Anderlecht | 0-2 |
| 2/4/23 9:00 AM | KSV Cercle Brügge | Standard Liège | 1-1 |
| 2/4/23 11:15 AM | KAS Eupen | KVC Westerlo | 1-1 |
| 2/4/23 11:15 AM | RFC Seraing | OH Leuven | 2-1 |
| 2/4/23 1:45 PM | Sint-Truidense VV | KV Kortrijk | 1-0 |
| 2/5/23 6:30 AM | Royal Antwerp FC | Club Brugge | 0-0 |
| 2/5/23 9:00 AM | KV Mechelen | Sporting Charleroi | 2-2 |
| 2/5/23 11:30 AM | KAA Gent | KRC Genk | 2-3 |
| 2/5/23 12:15 PM | Royale Union Saint-Gilloise | SV Zulte-Waregem | 4-0 |