| Date | Home | Away | Result |
|---|---|---|---|
| 1/27/23 1:45 PM | Standard Liège | KAS Eupen | 3-1 |
| 1/28/23 9:00 AM | KVC Westerlo | KV Mechelen | 2-0 |
| 1/28/23 11:15 AM | KV Kortrijk | KV Oostende | 2-2 |
| 1/28/23 11:15 AM | OH Leuven | Sint-Truidense VV | 1-1 |
| 1/28/23 1:45 PM | Sporting Charleroi | Royale Union Saint-Gilloise | 0-1 |
| 1/29/23 6:30 AM | RSC Anderlecht | Royal Antwerp FC | 0-0 |
| 1/29/23 9:00 AM | KSV Cercle Brügge | KAA Gent | 3-2 |
| 1/29/23 11:30 AM | SV Zulte-Waregem | Club Brugge | 1-2 |
| 1/29/23 2:00 PM | KRC Genk | RFC Seraing | 4-0 |