| Date | Home | Away | Result |
|---|---|---|---|
| 1/17/23 11:30 AM | OH Leuven | KAS Eupen | 1-1 |
| 1/17/23 1:45 PM | KVC Westerlo | KRC Genk | 2-3 |
| 1/17/23 1:45 PM | Standard Liège | KV Mechelen | 2-0 |
| 1/18/23 11:30 AM | KSV Cercle Brügge | Royale Union Saint-Gilloise | 1-1 |
| 1/18/23 11:30 AM | KV Oostende | Royal Antwerp FC | 0-3 |
| 1/18/23 1:45 PM | RSC Anderlecht | SV Zulte-Waregem | 2-3 |
| 1/18/23 1:45 PM | KV Kortrijk | RFC Seraing | 3-2 |
| 1/19/23 11:30 AM | KAA Gent | Sporting Charleroi | 0-0 |
| 1/19/23 1:45 PM | Sint-Truidense VV | Club Brugge | 1-1 |