| Date | Home | Away | Result |
|---|---|---|---|
| 8/1/25 1:45 PM | KV Mechelen | Club Brugge | 2-1 |
| 8/2/25 9:00 AM | KVC Westerlo | SV Zulte-Waregem | 3-1 |
| 8/2/25 11:15 AM | Standard Liège | FCV Dender EH | 1-1 |
| 8/2/25 1:45 PM | KAA Gent | RAAL La Louviere | 1-0 |
| 8/3/25 6:30 AM | KRC Genk | Royal Antwerp FC | 1-1 |
| 8/3/25 9:00 AM | KSV Cercle Brügge | RSC Anderlecht | 0-2 |
| 8/3/25 11:30 AM | Royale Union Saint-Gilloise | OH Leuven | 5-0 |
| 8/3/25 12:15 PM | Sporting Charleroi | Sint-Truidense VV | 1-1 |