| Date | Home | Away | Result |
|---|---|---|---|
| 10/24/25 1:45 PM | Sporting Charleroi | RSC Anderlecht | 1-0 |
| 10/25/25 9:00 AM | KVC Westerlo | FCV Dender EH | 1-1 |
| 10/25/25 11:15 AM | KV Mechelen | OH Leuven | 1-1 |
| 10/25/25 1:45 PM | KAA Gent | Standard Liège | 4-0 |
| 10/26/25 7:30 AM | Royal Antwerp FC | Club Brugge | 0-1 |
| 10/26/25 10:00 AM | KSV Cercle Brügge | SV Zulte-Waregem | 1-1 |
| 10/26/25 12:30 PM | KRC Genk | RAAL La Louviere | 1-1 |
| 10/26/25 1:15 PM | Royale Union Saint-Gilloise | Sint-Truidense VV | 2-0 |