| Date | Home | Away | Result |
|---|---|---|---|
| 10/18/25 9:00 AM | RAAL La Louviere | KVC Westerlo | 0-0 |
| 10/18/25 11:15 AM | OH Leuven | Club Brugge | 0-1 |
| 10/18/25 1:45 PM | Royale Union Saint-Gilloise | Sporting Charleroi | 3-1 |
| 10/19/25 6:30 AM | KSV Cercle Brügge | KRC Genk | 2-2 |
| 10/19/25 9:00 AM | FCV Dender EH | KV Mechelen | 1-3 |
| 10/19/25 11:30 AM | Sint-Truidense VV | RSC Anderlecht | 2-2 |
| 10/19/25 12:15 PM | SV Zulte-Waregem | KAA Gent | 4-1 |
| 10/20/25 8:00 AM | Standard Liège | Royal Antwerp FC | 1-0 |