Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/2/25 7:15 PM | 10/2/25 7:15 PM | Los Angeles Rams | San Francisco 49ers | 23-26OT | 3 - 10 - 10 |
| 10/5/25 8:30 AM | 10/5/25 8:30 AM | Cleveland Browns | Minnesota Vikings | 17-21 | 10 - 10 - 3 |
| 10/5/25 12:00 PM | 10/5/25 12:00 PM | New York Jets | Dallas Cowboys | 22-37 | 7 - 10 - 3 |
| 10/5/25 12:00 PM | 10/5/25 12:00 PM | Philadelphia Eagles | Denver Broncos | 17-21 | 3 - 10 - 10 |
| 10/5/25 12:00 PM | 10/5/25 12:00 PM | Carolina Panthers | Miami Dolphins | 27-24 | 4 - 10 - 4 |
| 10/5/25 12:00 PM | 10/5/25 12:00 PM | Indianapolis Colts | Las Vegas Raiders | 40-6 | 3 - 10 - 9 |
| 10/5/25 12:00 PM | 10/5/25 12:00 PM | New Orleans Saints | New York Giants | 26-14 | 4 - 10 - 4 |
| 10/5/25 12:00 PM | 10/5/25 12:00 PM | Baltimore Ravens | Houston Texans | 10-44 | 3 - 10 - 5 |
| 10/5/25 3:05 PM | 10/5/25 3:05 PM | Arizona Cardinals | Tennessee Titans | 21-22 | 3 - 10 - 10 |
| 10/5/25 3:05 PM | 10/5/25 3:05 PM | Seattle Seahawks | Tampa Bay Buccaneers | 35-38 | 4 - 10 - 5 |
| 10/5/25 3:25 PM | 10/5/25 3:25 PM | Cincinnati Bengals | Detroit Lions | 24-37 | 10 - 10 - 3 |
| 10/5/25 3:25 PM | 10/5/25 3:25 PM | Los Angeles Chargers | Washington Commanders | 10-27 | 3 - 10 - 6 |
| 10/5/25 7:20 PM | 10/5/25 7:20 PM | Buffalo Bills | New England Patriots | 20-23 | 3 - 10 - 10 |
| 10/6/25 7:15 PM | 10/6/25 7:15 PM | Jacksonville Jaguars | Kansas City Chiefs | 31-28 | 9 - 10 - 3 |