Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/4/25 7:20 PM | 9/4/25 7:20 PM | Philadelphia Eagles | Dallas Cowboys | 24-20 | 3 - 10 - 10 |
| 9/5/25 7:00 PM | 9/5/25 7:00 PM | Los Angeles Chargers | Kansas City Chiefs | 27-21 | 6 - 10 - 3 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | New England Patriots | Las Vegas Raiders | 13-20 | 3 - 10 - 6 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | Atlanta Falcons | Tampa Bay Buccaneers | 20-23 | 5 - 10 - 4 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | New York Jets | Pittsburgh Steelers | 32-34 | 7 - 10 - 3 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | New Orleans Saints | Arizona Cardinals | 13-20 | 7 - 10 - 3 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | Cleveland Browns | Cincinnati Bengals | 16-17 | 8 - 10 - 3 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | Jacksonville Jaguars | Carolina Panthers | 26-10 | 3 - 10 - 6 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | Indianapolis Colts | Miami Dolphins | 33-8 | 5 - 10 - 4 |
| 9/7/25 12:00 PM | 9/7/25 12:00 PM | Washington Commanders | New York Giants | 21-6 | 3 - 10 - 8 |
| 9/7/25 3:05 PM | 9/7/25 3:05 PM | Seattle Seahawks | San Francisco 49ers | 13-17 | 6 - 10 - 3 |
| 9/7/25 3:05 PM | 9/7/25 3:05 PM | Denver Broncos | Tennessee Titans | 20-12 | 3 - 10 - 10 |
| 9/7/25 3:25 PM | 9/7/25 3:25 PM | Green Bay Packers | Detroit Lions | 27-13 | 4 - 10 - 4 |
| 9/7/25 3:25 PM | 9/7/25 3:25 PM | Los Angeles Rams | Houston Texans | 14-9 | 3 - 10 - 7 |
| 9/7/25 7:20 PM | 9/7/25 7:20 PM | Buffalo Bills | Baltimore Ravens | 41-40 | 4 - 10 - 4 |
| 9/8/25 7:15 PM | 9/8/25 7:15 PM | Chicago Bears | Minnesota Vikings | 24-27 | 5 - 10 - 4 |