Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/4/25 1:30 PM | 10/4/25 1:30 PM | D.C. United | Charlotte FC | 0-1 | 5 - 7 points |
| 10/4/25 1:30 PM | 10/4/25 1:30 PM | CF Montreal | Nashville SC | 1-1 | 5 - 7 points |
| 10/4/25 3:30 PM | 10/4/25 3:30 PM | FC Dallas | Los Angeles Galaxy | 2-1 | 5 - 7 points |
| 10/4/25 6:30 PM | 10/4/25 6:30 PM | Philadelphia Union | New York City FC | 1-0 | 5 - 7 points |
| 10/4/25 6:30 PM | 10/4/25 6:30 PM | Orlando City | Columbus Crew | 1-1 | 5 - 7 points |
| 10/4/25 6:30 PM | 10/4/25 6:30 PM | New York Red Bulls | Cincinnati FC | 0-1 | 5 - 7 points |
| 10/4/25 6:30 PM | 10/4/25 6:30 PM | Inter Miami CF | New England Revolution | 4-1 | 5 - 7 points |
| 10/4/25 7:30 PM | 10/4/25 7:30 PM | Chicago Fire | Toronto FC | 2-2 | 5 - 7 points |
| 10/4/25 7:30 PM | 10/4/25 7:30 PM | Austin FC | St. Louis City SC | 1-3 | 5 - 7 points |
| 10/4/25 7:30 PM | 10/4/25 7:30 PM | Minnesota United FC | Sporting Kansas City | 3-0 | 5 - 7 points |
| 10/4/25 7:30 PM | 10/4/25 7:30 PM | Houston Dynamo | San Diego FC | 2-4 | 5 - 7 points |
| 10/4/25 8:30 PM | 10/4/25 8:30 PM | Real Salt Lake | Colorado Rapids | 1-0 | 5 - 7 points |
| 10/4/25 9:30 PM | 10/4/25 9:30 PM | Seattle Sounders | Portland Timbers | 1-0 | 5 - 7 points |
| 10/5/25 5:00 PM | 10/5/25 5:00 PM | Vancouver Whitecaps | San Jose Earthquakes | 4-1 | 5 - 7 points |
| 10/5/25 8:00 PM | 10/5/25 8:00 PM | Los Angeles FC | Atlanta United FC | 1-0 | 5 - 7 points |