Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/3/21 6:30 PM | 11/3/21 6:30 PM | CF Montreal | Houston Dynamo | 2-0 | 5 - 7 points |
| 11/3/21 6:30 PM | 11/3/21 6:30 PM | New York Red Bulls | Atlanta United FC | 0-0 | 5 - 7 points |
| 11/3/21 8:00 PM | 11/3/21 8:00 PM | Austin FC | Sporting Kansas City | 3-1 | 5 - 7 points |
| 11/3/21 9:30 PM | 11/3/21 9:30 PM | Real Salt Lake | Portland Timbers | 1-3 | 5 - 7 points |