Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 8/19/22 9:00 PM | 8/19/22 9:00 PM | Los Angeles Galaxy | Seattle Sounders | 3-3 | 5 - 7 points |
| 8/20/22 5:00 PM | 8/20/22 5:00 PM | New York Red Bulls | Cincinnati FC | 1-1 | 5 - 7 points |
| 8/20/22 6:30 PM | 8/20/22 6:30 PM | CF Montreal | New England Revolution | 4-0 | 5 - 7 points |
| 8/20/22 6:30 PM | 8/20/22 6:30 PM | D.C. United | Philadelphia Union | 0-6 | 5 - 7 points |
| 8/20/22 7:00 PM | 8/20/22 7:00 PM | Inter Miami CF | Toronto FC | 2-1 | 5 - 7 points |
| 8/20/22 7:00 PM | 8/20/22 7:00 PM | Minnesota United FC | Austin FC | 2-1 | 5 - 7 points |
| 8/20/22 8:00 PM | 8/20/22 8:00 PM | Colorado Rapids | Houston Dynamo | 1-1 | 5 - 7 points |
| 8/20/22 9:00 PM | 8/20/22 9:00 PM | Real Salt Lake | Vancouver Whitecaps | 1-1 | 5 - 7 points |
| 8/20/22 9:00 PM | 8/20/22 9:00 PM | San Jose Earthquakes | Los Angeles FC | 2-1 | 5 - 7 points |
| 8/21/22 4:30 PM | 8/21/22 4:30 PM | Columbus Crew | Atlanta United FC | 2-2 | 5 - 7 points |
| 8/21/22 5:00 PM | 8/21/22 5:00 PM | Chicago Fire | New York City FC | 0-2 | 5 - 7 points |
| 8/21/22 6:00 PM | 8/21/22 6:00 PM | Charlotte FC | Orlando City | 1-2 | 5 - 7 points |
| 8/21/22 6:30 PM | 8/21/22 6:30 PM | Sporting Kansas City | Portland Timbers | 4-1 | 5 - 7 points |
| 8/21/22 7:30 PM | 8/21/22 7:30 PM | Nashville SC | FC Dallas | 4-0 | 5 - 7 points |