Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 7/29/22 10:00 PM | 7/29/22 10:00 PM | Los Angeles FC | Seattle Sounders | 2-1 | 5 - 7 points |
| 7/30/22 2:00 PM | 7/30/22 2:00 PM | Minnesota United FC | Portland Timbers | 4-4 | 5 - 7 points |
| 7/30/22 4:00 PM | 7/30/22 4:00 PM | Chicago Fire | Atlanta United FC | 0-0 | 5 - 7 points |
| 7/30/22 6:30 PM | 7/30/22 6:30 PM | CF Montreal | New York City FC | 0-0 | 5 - 7 points |
| 7/30/22 6:30 PM | 7/30/22 6:30 PM | Philadelphia Union | Houston Dynamo | 6-0 | 5 - 7 points |
| 7/30/22 7:00 PM | 7/30/22 7:00 PM | New England Revolution | Toronto FC | 0-0 | 5 - 7 points |
| 7/30/22 7:00 PM | 7/30/22 7:00 PM | Inter Miami CF | Cincinnati FC | 4-4 | 5 - 7 points |
| 7/30/22 7:00 PM | 7/30/22 7:00 PM | Nashville SC | Vancouver Whitecaps | 1-1 | 5 - 7 points |
| 7/30/22 7:30 PM | 7/30/22 7:30 PM | Sporting Kansas City | Austin FC | 0-2 | 5 - 7 points |
| 7/30/22 8:00 PM | 7/30/22 8:00 PM | FC Dallas | Los Angeles Galaxy | 1-0 | 5 - 7 points |
| 7/30/22 9:00 PM | 7/30/22 9:00 PM | San Jose Earthquakes | Real Salt Lake | 2-2 | 5 - 7 points |
| 7/31/22 4:00 PM | 7/31/22 4:00 PM | D.C. United | Orlando City | 2-1 | 5 - 7 points |
| 8/2/22 6:30 PM | 8/2/22 6:30 PM | New York Red Bulls | Colorado Rapids | 4-5 | 5 - 7 points |
| 10/5/22 6:00 PM | 10/5/22 6:00 PM | Charlotte FC | Columbus Crew | 2-2 | 5 - 7 points |