Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 7/23/22 6:00 PM | 7/23/22 6:00 PM | New York City FC | Inter Miami CF | 2-0 | 5 - 7 points |
| 7/23/22 6:30 PM | 7/23/22 6:30 PM | Toronto FC | Charlotte FC | 4-0 | 5 - 7 points |
| 7/23/22 6:30 PM | 7/23/22 6:30 PM | Cincinnati FC | Nashville SC | 1-1 | 5 - 7 points |
| 7/23/22 6:30 PM | 7/23/22 6:30 PM | Columbus Crew | New England Revolution | 0-0 | 5 - 7 points |
| 7/23/22 6:30 PM | 7/23/22 6:30 PM | Orlando City | Philadelphia Union | 0-1 | 5 - 7 points |
| 7/23/22 7:00 PM | 7/23/22 7:00 PM | D.C. United | CF Montreal | 1-2 | 5 - 7 points |
| 7/23/22 7:30 PM | 7/23/22 7:30 PM | Houston Dynamo | Minnesota United FC | 1-2 | 5 - 7 points |
| 7/23/22 7:30 PM | 7/23/22 7:30 PM | Sporting Kansas City | Los Angeles FC | 0-2 | 5 - 7 points |
| 7/23/22 9:00 PM | 7/23/22 9:00 PM | Seattle Sounders | Colorado Rapids | 2-1 | 5 - 7 points |
| 7/23/22 9:00 PM | 7/23/22 9:00 PM | Vancouver Whitecaps | Chicago Fire | 1-3 | 5 - 7 points |
| 7/23/22 9:00 PM | 7/23/22 9:00 PM | Real Salt Lake | FC Dallas | 0-1 | 5 - 7 points |
| 7/23/22 9:30 PM | 7/23/22 9:30 PM | Portland Timbers | San Jose Earthquakes | 2-1 | 5 - 7 points |
| 7/24/22 7:00 PM | 7/24/22 7:00 PM | Austin FC | New York Red Bulls | 3-4 | 5 - 7 points |
| 7/24/22 8:30 PM | 7/24/22 8:30 PM | Los Angeles Galaxy | Atlanta United FC | 2-0 | 5 - 7 points |