Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 7/2/22 6:30 PM | 7/2/22 6:30 PM | Toronto FC | Seattle Sounders | 0-2 | 5 - 7 points |
| 7/2/22 9:00 PM | 7/2/22 9:00 PM | Vancouver Whitecaps | Los Angeles FC | 1-0 | 5 - 7 points |
| 7/3/22 4:00 PM | 7/3/22 4:00 PM | New York City FC | Atlanta United FC | 2-2 | 5 - 7 points |
| 7/3/22 6:30 PM | 7/3/22 6:30 PM | Columbus Crew | Philadelphia Union | 0-0 | 5 - 7 points |
| 7/3/22 6:30 PM | 7/3/22 6:30 PM | New England Revolution | Cincinnati FC | 2-2 | 5 - 7 points |
| 7/3/22 7:00 PM | 7/3/22 7:00 PM | Minnesota United FC | Real Salt Lake | 3-2 | 5 - 7 points |
| 7/3/22 7:00 PM | 7/3/22 7:00 PM | Sporting Kansas City | New York Red Bulls | 0-1 | 5 - 7 points |
| 7/3/22 7:30 PM | 7/3/22 7:30 PM | Nashville SC | Portland Timbers | 2-2 | 5 - 7 points |
| 7/3/22 7:30 PM | 7/3/22 7:30 PM | Houston Dynamo | Charlotte FC | 1-2 | 5 - 7 points |
| 7/3/22 8:00 PM | 7/3/22 8:00 PM | San Jose Earthquakes | Chicago Fire | 2-1 | 5 - 7 points |
| 7/4/22 6:00 PM | 7/4/22 6:00 PM | Orlando City | D.C. United | 3-5 | 5 - 7 points |
| 7/4/22 8:00 PM | 7/4/22 8:00 PM | Colorado Rapids | Austin FC | 2-3 | 5 - 7 points |
| 7/4/22 8:00 PM | 7/4/22 8:00 PM | FC Dallas | Inter Miami CF | 1-1 | 5 - 7 points |
| 7/4/22 9:30 PM | 7/4/22 9:30 PM | Los Angeles Galaxy | CF Montreal | 4-0 | 5 - 7 points |