Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 6/24/22 6:30 PM | 6/24/22 6:30 PM | Cincinnati FC | Orlando City | 1-0 | 5 - 7 points |
| 6/25/22 2:00 PM | 6/25/22 2:00 PM | Seattle Sounders | Sporting Kansas City | 3-0 | 5 - 7 points |
| 6/25/22 4:00 PM | 6/25/22 4:00 PM | D.C. United | Nashville SC | 1-3 | 5 - 7 points |
| 6/25/22 6:30 PM | 6/25/22 6:30 PM | CF Montreal | Charlotte FC | 2-1 | 5 - 7 points |
| 6/25/22 6:30 PM | 6/25/22 6:30 PM | Toronto FC | Atlanta United FC | 2-1 | 5 - 7 points |
| 6/25/22 7:00 PM | 6/25/22 7:00 PM | Houston Dynamo | Chicago Fire | 2-0 | 5 - 7 points |
| 6/25/22 7:00 PM | 6/25/22 7:00 PM | Inter Miami CF | Minnesota United FC | 2-1 | 5 - 7 points |
| 6/25/22 8:00 PM | 6/25/22 8:00 PM | Austin FC | FC Dallas | 2-2 | 5 - 7 points |
| 6/25/22 9:00 PM | 6/25/22 9:00 PM | Real Salt Lake | Columbus Crew | 0-0 | 5 - 7 points |
| 6/25/22 9:30 PM | 6/25/22 9:30 PM | Portland Timbers | Colorado Rapids | 3-0 | 5 - 7 points |
| 6/26/22 2:00 PM | 6/26/22 2:00 PM | Los Angeles FC | New York Red Bulls | 2-0 | 5 - 7 points |
| 6/26/22 5:00 PM | 6/26/22 5:00 PM | Philadelphia Union | New York City FC | 2-1 | 5 - 7 points |
| 6/26/22 7:00 PM | 6/26/22 7:00 PM | Vancouver Whitecaps | New England Revolution | 0-0 | 5 - 7 points |
| 9/24/22 9:00 PM | 9/24/22 9:00 PM | San Jose Earthquakes | Los Angeles Galaxy | 2-3 | 5 - 7 points |