Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 4/29/22 1:30 PM | 4/29/22 1:15 PM | 1. FC Union Berlin | SpVgg Greuther Fürth | 1-1 | 1 - 3 points |
| 4/30/22 8:30 AM | 4/29/22 1:15 PM | Arminia Bielefeld | Hertha BSC | 1-1 | 1 - 3 points |
| 4/30/22 8:30 AM | 4/29/22 1:15 PM | FC Augsburg | 1. FC Köln | 1-4 | 1 - 3 points |
| 4/30/22 8:30 AM | 4/29/22 1:15 PM | FSV Mainz 05 | FC Bayern Munich | 3-1 | 1 - 3 points |
| 4/30/22 8:30 AM | 4/29/22 1:15 PM | VfB Stuttgart | VfL Wolfsburg | 1-1 | 1 - 3 points |
| 4/30/22 8:30 AM | 4/29/22 1:15 PM | Borussia Dortmund | VfL Bochum | 3-4 | 1 - 3 points |
| 4/30/22 11:30 AM | 4/29/22 1:15 PM | 1899 Hoffenheim | SC Freiburg | 3-4 | 1 - 3 points |
| 5/2/22 1:30 PM | 4/29/22 1:15 PM | Bor. Mönchengladbach | RB Leipzig | 3-1 | 1 - 3 points |
| 5/2/22 1:30 PM | 4/29/22 1:15 PM | Bayer 04 Leverkusen | Eintracht Frankfurt | 2-0 | 1 - 3 points |