| Date | Home | Away | Result |
|---|---|---|---|
| 4/4/26 12:00 PM | Toronto FC | Colorado Rapids | 3-2 |
| 4/4/26 3:30 PM | New England Revolution | CF Montreal | 3-0 |
| 4/4/26 3:30 PM | Real Salt Lake | Sporting Kansas City | 3-1 |
| 4/4/26 6:30 PM | Charlotte FC | Philadelphia Union | 2-1 |
| 4/4/26 6:30 PM | New York City FC | St. Louis City SC | 1-1 |
| 4/4/26 6:30 PM | Atlanta United FC | Columbus Crew | 1-3 |
| 4/4/26 6:30 PM | D.C. United | FC Dallas | 0-4 |
| 4/4/26 6:30 PM | New York Red Bulls | Cincinnati FC | 4-2 |
| 4/4/26 7:00 PM | Inter Miami CF | Austin FC | 2-2 |
| 4/4/26 7:30 PM | Houston Dynamo | Seattle Sounders | 0-1 |
| 4/4/26 7:30 PM | Chicago Fire | Nashville SC | 1-0 |
| 4/4/26 8:30 PM | Los Angeles FC | Orlando City | 6-0 |
| 4/4/26 9:30 PM | San Jose Earthquakes | San Diego FC | 3-0 |
| 4/4/26 9:30 PM | Vancouver Whitecaps | Portland Timbers | 3-2 |
| 4/4/26 9:30 PM | Los Angeles Galaxy | Minnesota United FC | 1-2 |