| Date | Home | Away | Result |
|---|---|---|---|
| 9/9/26 6:30 PM | Toronto FC | Nashville SC | 2-1 |
| 9/9/26 6:30 PM | CF Montreal | Charlotte FC | 1-2 |
| 9/9/26 6:30 PM | D.C. United | Columbus Crew | 2-1 |
| 9/9/26 6:30 PM | Atlanta United FC | Orlando City | 2-3 |
| 9/9/26 6:45 PM | Philadelphia Union | Cincinnati FC | 5-0 |
| 9/9/26 7:00 PM | New York City FC | New England Revolution | 1-2 |
| 9/9/26 7:30 PM | Chicago Fire | Inter Miami CF | 1-1 |
| 9/9/26 7:30 PM | Austin FC | Colorado Rapids | 1-1 |
| 9/9/26 7:30 PM | Houston Dynamo | Real Salt Lake | 2-1 |
| 9/9/26 7:30 PM | Minnesota United FC | FC Dallas | 1-2 |
| 9/9/26 9:30 PM | Los Angeles FC | New York Red Bulls | 2-0 |
| 9/9/26 9:30 PM | Portland Timbers | St. Louis City SC | 2-2 |
| 9/9/26 9:30 PM | Vancouver Whitecaps | Los Angeles Galaxy | 3-0 |
| 9/9/26 9:30 PM | San Diego FC | San Jose Earthquakes | 2-3 |
| 10/1/26 8:30 PM | Seattle Sounders | Sporting Kansas City | 2-1 |