| Date | Home | Away | Result |
|---|---|---|---|
| 5/16/26 3:30 PM | CF Montreal | Chicago Fire | 0-2 |
| 5/16/26 6:30 PM | New York Red Bulls | New York City FC | 1-1 |
| 5/16/26 6:30 PM | Philadelphia Union | Columbus Crew | 1-1 |
| 5/16/26 6:30 PM | Orlando City | Atlanta United FC | 1-1 |
| 5/16/26 6:30 PM | New England Revolution | Minnesota United FC | 2-1 |
| 5/16/26 6:30 PM | D.C. United | St. Louis City SC | 1-1 |
| 5/16/26 6:30 PM | Charlotte FC | Toronto FC | 3-1 |
| 5/16/26 7:30 PM | Austin FC | Sporting Kansas City | 1-2 |
| 5/16/26 7:30 PM | Houston Dynamo | Vancouver Whitecaps | 1-0 |
| 5/16/26 8:15 PM | Seattle Sounders | Los Angeles Galaxy | 0-2 |
| 5/16/26 8:30 PM | Real Salt Lake | Colorado Rapids | 2-1 |
| 5/16/26 8:30 PM | San Diego FC | Cincinnati FC | 3-3 |
| 5/16/26 9:30 PM | San Jose Earthquakes | FC Dallas | 2-3 |
| 5/17/26 5:00 PM | Inter Miami CF | Portland Timbers | 2-0 |
| 5/17/26 7:00 PM | Nashville SC | Los Angeles FC | 3-2 |