| Date | Home | Away | Result |
|---|---|---|---|
| 5/13/26 6:15 PM | Charlotte FC | New York City FC | 0-1 |
| 5/13/26 6:30 PM | New England Revolution | Nashville SC | 0-3 |
| 5/13/26 6:30 PM | CF Montreal | Portland Timbers | 2-2 |
| 5/13/26 6:30 PM | Cincinnati FC | Inter Miami CF | 3-5 |
| 5/13/26 6:30 PM | Orlando City | Philadelphia Union | 4-3 |
| 5/13/26 6:30 PM | New York Red Bulls | Columbus Crew | 3-2 |
| 5/13/26 6:30 PM | D.C. United | Chicago Fire | 1-3 |
| 5/13/26 7:30 PM | FC Dallas | Vancouver Whitecaps | 2-3 |
| 5/13/26 7:30 PM | Sporting Kansas City | Los Angeles Galaxy | 3-1 |
| 5/13/26 7:30 PM | Minnesota United FC | Colorado Rapids | 0-1 |
| 5/13/26 7:30 PM | St. Louis City SC | Los Angeles FC | 2-1 |
| 5/13/26 8:30 PM | Seattle Sounders | San Jose Earthquakes | 3-2 |
| 5/13/26 8:30 PM | San Diego FC | Austin FC | 5-0 |
| 5/13/26 8:30 PM | Real Salt Lake | Houston Dynamo | 3-0 |