| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 5/5/26 5:00 PM | Sporting Cristal | Palmeiras | Group F | 0-2 |
| 5/5/26 5:00 PM | Rosario Central | Club Libertad | Group H | 1-0 |
| 5/5/26 7:00 PM | Barcelona SC | Boca Juniors | Group D | 1-0 |
| 5/5/26 7:00 PM | Universidad Central | Independiente del Valle | Group H | 2-0 |
| 5/5/26 7:30 PM | Always Ready | CA Lanus | Group G | 4-0 |
| 5/6/26 5:00 PM | Cusco FC | Estudiantes de La Plata | Group A | 1-1 |
| 5/6/26 5:00 PM | Deportivo La Guaira | Club Bolívar | Group C | 1-1 |
| 5/6/26 7:30 PM | Independiente Rivadavia | Fluminense | Group C | 1-1 |
| 5/6/26 7:30 PM | Union Santa Fe | Corinthians | Group E | 1-1 |
| 5/6/26 9:00 PM | Deportes Tolima | Club Nacional de Football | Group B | 3-0 |
| 5/6/26 9:00 PM | Universidad Católica | Cruzeiro | Group D | 0-0 |
| 5/7/26 5:00 PM | CA Platense | Club Atlético Peñarol | Group E | 1-1 |
| 5/7/26 5:00 PM | Mirassol FC | LDU Quito | Group G | 2-0 |
| 5/7/26 7:00 PM | Coquimbo Unido | Universitario | Group B | 2-1 |
| 5/7/26 7:30 PM | Independiente Medellín | Flamengo | Group A | 0-3 |
| 5/7/26 9:00 PM | Junior FC | Club Cerro Porteno | Group F | 0-1 |