| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 4/7/26 5:00 PM | Independiente Rivadavia | Club Bolívar | Group C | 1-0 |
| 4/7/26 5:00 PM | Deportivo La Guaira | Fluminense | Group C | 0-0 |
| 4/7/26 7:00 PM | Barcelona SC | Cruzeiro | Group D | 0-1 |
| 4/7/26 7:00 PM | Always Ready | LDU Quito | Group G | 0-1 |
| 4/7/26 7:30 PM | Universidad Católica | Boca Juniors | Group D | 1-2 |
| 4/7/26 9:00 PM | Deportes Tolima | Universitario | Group B | 0-0 |
| 4/8/26 5:00 PM | Coquimbo Unido | Club Nacional de Football | Group B | 1-1 |
| 4/8/26 5:00 PM | Mirassol FC | CA Lanus | Group G | 1-0 |
| 4/8/26 7:00 PM | Independiente Medellín | Estudiantes de La Plata | Group A | 1-1 |
| 4/8/26 7:30 PM | Junior FC | Palmeiras | Group F | 1-1 |
| 4/8/26 7:30 PM | Cusco FC | Flamengo | Group A | 0-2 |
| 4/8/26 9:00 PM | Sporting Cristal | Club Cerro Porteno | Group F | 1-0 |
| 4/9/26 5:00 PM | Rosario Central | Independiente del Valle | Group H | 0-0 |
| 4/9/26 5:00 PM | Universidad Central | Club Libertad | Group H | 3-1 |
| 4/9/26 7:00 PM | CA Platense | Corinthians | Group E | 0-2 |
| 4/9/26 9:00 PM | Union Santa Fe | Club Atlético Peñarol | Group E | 1-1 |