| Date | Home | Away | Result |
|---|---|---|---|
| 10/4/25 8:00 AM | AC Monza | US Catanzaro 1929 | 2-1 |
| 10/4/25 8:00 AM | FC Venice | Frosinone Calcio | 3-0 |
| 10/4/25 8:00 AM | US Avellino | Mantova 1911 | 0-0 |
| 10/4/25 8:00 AM | SSC Bari | Padova Calcio | 2-1 |
| 10/4/25 10:15 AM | Spezia Calcio | Palermo FC | 1-2 |
| 10/4/25 12:30 PM | FC Cesena | AC Reggiana 1919 | 1-2 |
| 10/5/25 8:00 AM | Carrarese Calcio 1908 | Juve Stabia | 3-0 |
| 10/5/25 8:00 AM | FC Südtirol | FC Empoli | 1-2 |
| 10/5/25 10:15 AM | Sampdoria Genua | Pescara Calcio | 4-1 |
| 10/5/25 12:30 PM | Modena FC | Virtus Entella | 2-0 |
| 10/18/25 8:00 AM | US Lecce | Sassuolo Calcio | 0-0 |
| 10/18/25 8:00 AM | Pisa Sporting Club | Hellas Verona | 0-0 |
| 10/18/25 11:00 AM | FC Turin | SSC Napoli | 1-0 |
| 10/18/25 1:45 PM | AS Roma | Inter Milan | 0-1 |
| 10/19/25 5:30 AM | Como Calcio | Juventus Turin | 2-0 |
| 10/19/25 8:00 AM | Cagliari Calcio | FC Bologna | 0-2 |
| 10/19/25 8:00 AM | Genua CFC | Parma Calcio 1913 | 0-0 |
| 10/19/25 11:00 AM | Atalanta Bergamo | Lazio Rom | 0-0 |
| 10/19/25 1:45 PM | AC Milan | Fiorentina | 2-1 |
| 10/20/25 1:45 PM | US Cremonese | Udinese Calcio | 1-1 |