| Date | Home | Away | Result |
|---|---|---|---|
| 9/23/25 10:00 AM | Cagliari Calcio | Frosinone Calcio | 4-1 |
| 9/23/25 11:30 AM | Udinese Calcio | Palermo FC | 2-1 |
| 9/23/25 2:00 PM | AC Milan | US Lecce | 3-0 |
| 9/24/25 10:00 AM | Parma Calcio 1913 | Spezia Calcio | 6-5a.PSO/2-2FT |
| 9/24/25 11:30 AM | Hellas Verona | FC Venice | 4-5a.PSO/0-0FT |
| 9/24/25 2:00 PM | Como Calcio | Sassuolo Calcio | 3-0 |
| 9/25/25 11:30 AM | Genua CFC | FC Empoli | 3-1 |
| 9/25/25 2:00 PM | FC Turin | Pisa Sporting Club | 1-0 |
| 9/30/25 1:30 PM | Palermo FC | FC Venice | 0-0 |
| 9/30/25 1:30 PM | Juve Stabia | Mantova 1911 | 2-1 |
| 9/30/25 1:30 PM | Padova Calcio | US Avellino | 2-2 |
| 9/30/25 1:30 PM | AC Reggiana 1919 | Spezia Calcio | 1-1 |
| 9/30/25 1:30 PM | Virtus Entella | SSC Bari | 2-2 |
| 9/30/25 1:30 PM | Frosinone Calcio | FC Cesena | 3-1 |
| 10/1/25 1:30 PM | Pescara Calcio | FC Südtirol | 1-1 |
| 10/1/25 1:30 PM | Sampdoria Genua | US Catanzaro 1929 | 0-0 |
| 10/1/25 1:30 PM | Carrarese Calcio 1908 | Modena FC | 0-0 |
| 10/1/25 1:30 PM | FC Empoli | AC Monza | 1-1 |
| 10/3/25 1:45 PM | Hellas Verona | Sassuolo Calcio | 0-1 |
| 10/4/25 8:00 AM | Lazio Rom | FC Turin | 3-3 |
| 10/4/25 8:00 AM | Parma Calcio 1913 | US Lecce | 0-1 |
| 10/4/25 11:00 AM | Inter Milan | US Cremonese | 4-1 |
| 10/4/25 1:45 PM | Atalanta Bergamo | Como Calcio | 1-1 |
| 10/5/25 5:30 AM | Udinese Calcio | Cagliari Calcio | 1-1 |
| 10/5/25 8:00 AM | FC Bologna | Pisa Sporting Club | 4-0 |
| 10/5/25 8:00 AM | Fiorentina | AS Roma | 1-2 |
| 10/5/25 11:00 AM | SSC Napoli | Genua CFC | 2-1 |
| 10/5/25 1:45 PM | Juventus Turin | AC Milan | 0-0 |