| Date | Home | Away | Result |
|---|---|---|---|
| 2/21/26 8:00 AM | Virtus Entella | US Catanzaro 1929 | --- |
| 2/21/26 8:00 AM | Frosinone Calcio | FC Empoli | --- |
| 2/21/26 8:00 AM | Carrarese Calcio 1908 | AC Monza | --- |
| 2/21/26 8:00 AM | FC Cesena | Spezia Calcio | --- |
| 2/21/26 8:00 AM | Padova Calcio | SSC Bari | --- |
| 2/21/26 8:00 AM | Palermo FC | FC Südtirol | --- |
| 2/21/26 8:00 AM | Juve Stabia | Modena FC | --- |
| 2/21/26 8:00 AM | Mantova 1911 | Sampdoria Genua | --- |
| 2/21/26 8:00 AM | AC Reggiana 1919 | US Avellino | --- |
| 2/21/26 8:00 AM | FC Venice | Pescara Calcio | --- |
| 2/22/26 11:00 AM | FC Bologna | Udinese Calcio | --- |
| 2/22/26 11:00 AM | Atalanta Bergamo | SSC Napoli | --- |
| 2/22/26 11:00 AM | Fiorentina | Pisa Sporting Club | --- |
| 2/22/26 11:00 AM | Cagliari Calcio | Lazio Rom | --- |
| 2/22/26 11:00 AM | Juventus Turin | Como Calcio | --- |
| 2/22/26 11:00 AM | Genua CFC | FC Turin | --- |
| 2/22/26 11:00 AM | AC Milan | Parma Calcio 1913 | --- |
| 2/22/26 11:00 AM | US Lecce | Inter Milan | --- |
| 2/22/26 11:00 AM | Sassuolo Calcio | Hellas Verona | --- |
| 2/22/26 11:00 AM | AS Roma | US Cremonese | --- |