| Date | Home | Away | Result |
|---|---|---|---|
| 11/21/25 1:30 PM | US Catanzaro 1929 | Pescara Calcio | 3-3 |
| 11/22/25 8:00 AM | US Avellino | FC Empoli | 0-3 |
| 11/22/25 8:00 AM | Virtus Entella | Palermo FC | 1-1 |
| 11/22/25 8:00 AM | Carrarese Calcio 1908 | AC Reggiana 1919 | 0-0 |
| 11/22/25 10:15 AM | Padova Calcio | FC Venice | 0-2 |
| 11/22/25 12:30 PM | SSC Bari | Frosinone Calcio | 2-3 |
| 11/23/25 8:00 AM | Mantova 1911 | Spezia Calcio | 4-1 |
| 11/23/25 8:00 AM | Modena FC | FC Südtirol | 0-0 |
| 11/23/25 10:15 AM | AC Monza | FC Cesena | 1-0 |
| 11/24/25 1:30 PM | Sampdoria Genua | Juve Stabia | 1-0 |
| 11/28/25 1:45 PM | Como Calcio | Sassuolo Calcio | 2-0 |
| 11/29/25 8:00 AM | Genua CFC | Hellas Verona | 2-1 |
| 11/29/25 8:00 AM | Parma Calcio 1913 | Udinese Calcio | 0-2 |
| 11/29/25 11:00 AM | Juventus Turin | Cagliari Calcio | 2-1 |
| 11/29/25 1:45 PM | AC Milan | Lazio Rom | 1-0 |
| 11/30/25 5:30 AM | US Lecce | FC Turin | 2-1 |
| 11/30/25 8:00 AM | Pisa Sporting Club | Inter Milan | 0-2 |
| 11/30/25 11:00 AM | Atalanta Bergamo | Fiorentina | 2-0 |
| 11/30/25 1:45 PM | AS Roma | SSC Napoli | 0-1 |
| 12/1/25 1:45 PM | FC Bologna | US Cremonese | 1-3 |