Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/28/21 12:05 PM | 10/28/21 12:05 PM | Rhein-Neckar-Löwen | HBW Balingen-Weilstetten | 34-23 | 1 - 4 points |
| 10/28/21 12:05 PM | 10/28/21 12:05 PM | TSV Hannover-Burgdorf | TSV GWD Minden | 30-29 | 1 - 4 points |
| 10/30/21 11:30 AM | 10/30/21 11:30 AM | Bergischer HC | SC DHfK Leipzig | 30-20 | 1 - 4 points |
| 10/30/21 1:30 PM | 10/30/21 1:30 PM | TuS N-Lübbecke | THW Kiel | 29-25 | 1 - 4 points |
| 10/31/21 8:00 AM | 10/31/21 8:00 AM | Frisch Auf Göppingen | SG Flensburg-Handewitt | 30-30 | 1 - 4 points |
| 10/31/21 10:00 AM | 10/31/21 10:00 AM | HSG Wetzlar | TVB 1898 Stuttgart | 35-34 | 1 - 4 points |
| 10/31/21 10:00 AM | 10/31/21 10:00 AM | TBV Lemgo | Füchse Berlin | 27-28 | 1 - 4 points |
| 10/31/21 10:00 AM | 10/31/21 10:00 AM | SC Magdeburg | HC Erlangen | 28-27 | 1 - 4 points |
| 11/28/21 11:05 AM | 11/28/21 11:05 AM | HSV Hamburg | MT Melsungen | 26-25 | 1 - 4 points |