Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/14/21 12:05 PM | 10/14/21 12:05 PM | TuS N-Lübbecke | HC Erlangen | 20-21 | 1 - 4 points |
| 10/14/21 12:05 PM | 10/14/21 12:05 PM | Frisch Auf Göppingen | MT Melsungen | 26-26 | 1 - 4 points |
| 10/14/21 12:05 PM | 10/14/21 12:05 PM | TSV Hannover-Burgdorf | Füchse Berlin | 22-25 | 1 - 4 points |
| 10/17/21 7:00 AM | 10/17/21 7:00 AM | SC Magdeburg | SG Flensburg-Handewitt | 33-28 | 1 - 4 points |
| 10/17/21 9:00 AM | 10/17/21 9:00 AM | HSV Hamburg | TSV GWD Minden | 31-27 | 1 - 4 points |
| 10/17/21 9:00 AM | 10/17/21 9:00 AM | TVB 1898 Stuttgart | HBW Balingen-Weilstetten | 27-26 | 1 - 4 points |
| 10/17/21 9:00 AM | 10/17/21 9:00 AM | TBV Lemgo | THW Kiel | 21-21 | 1 - 4 points |
| 11/23/21 11:30 AM | 11/23/21 11:30 AM | Bergischer HC | HSG Wetzlar | 17-27 | 1 - 4 points |
| 11/23/21 12:00 PM | 11/23/21 12:00 PM | Rhein-Neckar-Löwen | SC DHfK Leipzig | 28-28 | 1 - 4 points |