Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/26/21 7:00 AM | 9/26/21 7:00 AM | SC Magdeburg | SC DHfK Leipzig | 30-28 | 1 - 4 points |
| 9/30/21 12:05 PM | 9/30/21 12:05 PM | HSV Hamburg | HSG Wetzlar | 31-23 | 1 - 4 points |
| 9/30/21 12:05 PM | 9/30/21 12:05 PM | Frisch Auf Göppingen | Bergischer HC | 27-24 | 1 - 4 points |
| 9/30/21 12:05 PM | 9/30/21 12:05 PM | TBV Lemgo | HBW Balingen-Weilstetten | 38-28 | 1 - 4 points |
| 10/2/21 1:30 PM | 10/2/21 1:30 PM | TuS N-Lübbecke | SG Flensburg-Handewitt | 17-34 | 1 - 4 points |
| 10/3/21 7:00 AM | 10/3/21 7:00 AM | TSV Hannover-Burgdorf | MT Melsungen | 23-25 | 1 - 4 points |
| 10/3/21 9:00 AM | 10/3/21 9:00 AM | TVB 1898 Stuttgart | Rhein-Neckar-Löwen | 35-30 | 1 - 4 points |
| 10/3/21 9:00 AM | 10/3/21 9:00 AM | Füchse Berlin | HC Erlangen | 35-30 | 1 - 4 points |
| 10/3/21 9:00 AM | 10/3/21 9:00 AM | THW Kiel | TSV GWD Minden | 34-25 | 1 - 4 points |