Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/23/21 12:05 PM | 9/23/21 12:05 PM | HBW Balingen-Weilstetten | SC Magdeburg | 17-28 | 1 - 4 points |
| 9/23/21 12:05 PM | 9/23/21 12:05 PM | TSV GWD Minden | Füchse Berlin | 25-31 | 1 - 4 points |
| 9/23/21 12:05 PM | 9/23/21 12:05 PM | Bergischer HC | TVB 1898 Stuttgart | 26-25 | 1 - 4 points |
| 9/23/21 12:05 PM | 9/23/21 12:05 PM | SC DHfK Leipzig | HSV Hamburg | 27-27 | 1 - 4 points |
| 9/25/21 1:30 PM | 9/25/21 1:30 PM | HC Erlangen | THW Kiel | 20-30 | 1 - 4 points |
| 9/26/21 9:00 AM | 9/26/21 9:00 AM | HSG Wetzlar | TSV Hannover-Burgdorf | 38-16 | 1 - 4 points |
| 9/26/21 9:00 AM | 9/26/21 9:00 AM | MT Melsungen | TuS N-Lübbecke | 23-22 | 1 - 4 points |
| 9/26/21 9:00 AM | 9/26/21 9:00 AM | Rhein-Neckar-Löwen | Frisch Auf Göppingen | 37-32 | 1 - 4 points |
| 12/16/21 11:30 AM | 12/16/21 11:30 AM | SG Flensburg-Handewitt | TBV Lemgo | 27-19 | 1 - 4 points |