Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 5/5/22 12:05 PM | 5/5/22 12:05 PM | SC DHfK Leipzig | THW Kiel | 20-31 | 1 - 4 points |
| 5/5/22 12:05 PM | 5/5/22 12:05 PM | MT Melsungen | TSV Hannover-Burgdorf | 22-29 | 1 - 4 points |
| 5/5/22 12:05 PM | 5/5/22 12:05 PM | SG Flensburg-Handewitt | Frisch Auf Göppingen | 26-21 | 1 - 4 points |
| 5/7/22 11:30 AM | 5/7/22 11:30 AM | HSG Wetzlar | Füchse Berlin | 28-30 | 1 - 4 points |
| 5/7/22 1:30 PM | 5/7/22 1:30 PM | HC Erlangen | SC Magdeburg | 36-38 | 1 - 4 points |
| 5/8/22 7:00 AM | 5/8/22 7:00 AM | TSV GWD Minden | TVB 1898 Stuttgart | 25-26 | 1 - 4 points |
| 5/8/22 9:05 AM | 5/8/22 9:05 AM | HSV Hamburg | TuS N-Lübbecke | 32-24 | 1 - 4 points |
| 5/8/22 9:05 AM | 5/8/22 9:05 AM | HBW Balingen-Weilstetten | TBV Lemgo | 29-32 | 1 - 4 points |
| 5/8/22 9:05 AM | 5/8/22 9:05 AM | Rhein-Neckar-Löwen | Bergischer HC | 24-22 | 1 - 4 points |