Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/31/22 12:05 PM | 3/31/22 12:05 PM | TVB 1898 Stuttgart | HC Erlangen | 34-29 | 1 - 4 points |
| 3/31/22 12:05 PM | 3/31/22 12:05 PM | SC Magdeburg | TSV Hannover-Burgdorf | 30-22 | 1 - 4 points |
| 3/31/22 12:05 PM | 3/31/22 12:05 PM | Bergischer HC | Füchse Berlin | 23-28 | 1 - 4 points |
| 4/2/22 1:30 PM | 4/2/22 1:30 PM | Rhein-Neckar-Löwen | SG Flensburg-Handewitt | 29-29 | 1 - 4 points |
| 4/3/22 7:00 AM | 4/3/22 7:00 AM | TBV Lemgo | TSV GWD Minden | 20-32 | 1 - 4 points |
| 4/3/22 9:05 AM | 4/3/22 9:05 AM | Frisch Auf Göppingen | HBW Balingen-Weilstetten | 27-28 | 1 - 4 points |
| 4/3/22 9:05 AM | 4/3/22 9:05 AM | HSV Hamburg | SC DHfK Leipzig | 24-33 | 1 - 4 points |
| 4/3/22 9:05 AM | 4/3/22 9:05 AM | TuS N-Lübbecke | MT Melsungen | 23-31 | 1 - 4 points |
| 4/28/22 12:05 PM | 4/28/22 12:05 PM | THW Kiel | HSG Wetzlar | 27-24 | 1 - 4 points |