Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 3/3/22 12:05 PM | 3/3/22 12:05 PM | TSV Hannover-Burgdorf | TBV Lemgo | 27-31 | 1 - 4 points |
| 3/3/22 12:05 PM | 3/3/22 12:05 PM | TSV GWD Minden | Rhein-Neckar-Löwen | 31-33 | 1 - 4 points |
| 3/3/22 12:05 PM | 3/3/22 12:05 PM | TVB 1898 Stuttgart | HSG Wetzlar | 26-26 | 1 - 4 points |
| 3/3/22 12:05 PM | 3/3/22 12:05 PM | MT Melsungen | HSV Hamburg | 26-22 | 1 - 4 points |
| 3/6/22 7:00 AM | 3/6/22 7:00 AM | SC Magdeburg | Bergischer HC | 38-25 | 1 - 4 points |
| 3/6/22 9:00 AM | 3/6/22 9:00 AM | HBW Balingen-Weilstetten | THW Kiel | 25-31 | 1 - 4 points |
| 3/6/22 9:00 AM | 3/6/22 9:00 AM | HC Erlangen | TuS N-Lübbecke | 29-22 | 1 - 4 points |
| 3/6/22 9:00 AM | 3/6/22 9:00 AM | SC DHfK Leipzig | SG Flensburg-Handewitt | 25-24 | 1 - 4 points |
| 5/19/22 12:05 PM | 5/19/22 12:05 PM | Füchse Berlin | Frisch Auf Göppingen | 37-31 | 1 - 4 points |