Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 12/2/21 12:05 PM | 12/2/21 12:05 PM | TVB 1898 Stuttgart | TSV GWD Minden | 35-31 | 1 - 4 points |
| 12/2/21 12:05 PM | 12/2/21 12:05 PM | SC DHfK Leipzig | HBW Balingen-Weilstetten | 31-24 | 1 - 4 points |
| 12/4/21 11:30 AM | 12/4/21 11:30 AM | Bergischer HC | SG Flensburg-Handewitt | 24-29 | 1 - 4 points |
| 12/5/21 6:40 AM | 12/5/21 6:40 AM | HSV Hamburg | THW Kiel | 23-32 | 1 - 4 points |
| 12/5/21 9:00 AM | 12/5/21 9:00 AM | Frisch Auf Göppingen | HC Erlangen | 34-25 | 1 - 4 points |
| 12/5/21 9:00 AM | 12/5/21 9:00 AM | HSG Wetzlar | MT Melsungen | 31-28 | 1 - 4 points |
| 12/5/21 9:00 AM | 12/5/21 9:00 AM | TSV Hannover-Burgdorf | TuS N-Lübbecke | 22-21 | 1 - 4 points |
| 12/5/21 9:00 AM | 12/5/21 9:00 AM | SC Magdeburg | TBV Lemgo | 29-25 | 1 - 4 points |
| 3/27/22 9:05 AM | 3/27/22 9:05 AM | Rhein-Neckar-Löwen | Füchse Berlin | 24-29 | 1 - 4 points |