Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/13/21 8:30 AM | 11/13/21 8:30 AM | MT Melsungen | TVB 1898 Stuttgart | 29-23 | 1 - 4 points |
| 11/13/21 8:30 AM | 11/13/21 8:30 AM | TuS N-Lübbecke | TBV Lemgo | 26-28 | 1 - 4 points |
| 11/13/21 8:30 AM | 11/13/21 8:30 AM | TSV GWD Minden | Frisch Auf Göppingen | 30-33 | 1 - 4 points |
| 11/13/21 11:05 AM | 11/13/21 11:05 AM | Füchse Berlin | SC Magdeburg | 29-33 | 1 - 4 points |
| 11/13/21 11:05 AM | 11/13/21 11:05 AM | SG Flensburg-Handewitt | Rhein-Neckar-Löwen | 31-26 | 1 - 4 points |
| 11/14/21 7:00 AM | 11/14/21 7:00 AM | THW Kiel | TSV Hannover-Burgdorf | 31-24 | 1 - 4 points |
| 11/14/21 9:00 AM | 11/14/21 9:00 AM | HBW Balingen-Weilstetten | Bergischer HC | 30-28 | 1 - 4 points |
| 11/14/21 9:00 AM | 11/14/21 9:00 AM | HC Erlangen | HSV Hamburg | 23-22 | 1 - 4 points |
| 11/14/21 9:00 AM | 11/14/21 9:00 AM | SC DHfK Leipzig | HSG Wetzlar | 30-26 | 1 - 4 points |