Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/26/21 9:00 AM | 9/26/21 9:00 AM | TVB 1898 Stuttgart | HSV Hamburg | 26-34 | 1 - 4 points |
| 11/10/21 12:05 PM | 11/10/21 12:05 PM | Rhein-Neckar-Löwen | TBV Lemgo | 30-33 | 1 - 4 points |
| 11/10/21 12:05 PM | 11/10/21 12:05 PM | SG Flensburg-Handewitt | Füchse Berlin | 28-23 | 1 - 4 points |
| 11/10/21 12:05 PM | 11/10/21 12:05 PM | Frisch Auf Göppingen | SC Magdeburg | 24-25 | 1 - 4 points |
| 11/10/21 12:05 PM | 11/10/21 12:05 PM | HSG Wetzlar | TuS N-Lübbecke | 29-25 | 1 - 4 points |
| 11/10/21 12:05 PM | 11/10/21 12:05 PM | MT Melsungen | TSV GWD Minden | 25-29 | 1 - 4 points |
| 11/11/21 12:05 PM | 11/11/21 12:05 PM | HBW Balingen-Weilstetten | HC Erlangen | 23-25 | 1 - 4 points |
| 11/11/21 12:05 PM | 11/11/21 12:05 PM | THW Kiel | Bergischer HC | 24-23 | 1 - 4 points |
| 11/11/21 12:05 PM | 11/11/21 12:05 PM | SC DHfK Leipzig | TSV Hannover-Burgdorf | 32-25 | 1 - 4 points |