Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 1/7/22 2:00 PM | 1/7/22 2:00 PM | Swindon Town | Manchester City | 1-4 | 5 - 7 points |
| 1/8/22 6:15 AM | 1/8/22 6:15 AM | Mansfield Town | Middlesbrough FC | 2-3 | 5 - 7 points |
| 1/8/22 6:30 AM | 1/8/22 6:30 AM | Burnley FC | Huddersfield Town | 1-2 | 5 - 7 points |
| 1/8/22 6:30 AM | 1/8/22 6:30 AM | Bristol City | Fulham FC | 0-1a.e.t | 5 - 7 points |
| 1/8/22 6:30 AM | 1/8/22 6:30 AM | Hartlepool United | FC Blackpool | 2-1 | 5 - 7 points |
| 1/8/22 6:30 AM | 1/8/22 6:30 AM | Coventry City | Derby County | 1-0 | 5 - 7 points |
| 1/8/22 6:45 AM | 1/8/22 6:45 AM | Millwall FC | Crystal Palace | 1-2 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Boreham Wood | AFC Wimbledon | 2-0 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Peterborough United | Bristol Rovers | 2-1 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Leicester City | Watford FC | 4-1 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | FC Port Vale | Brentford FC | 1-4 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Queens Park Rangers | Rotherham United | 9-8a.PSO | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Barnsley FC | Barrow FC | 5-4a.e.t | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Kidderminster Harriers | Reading FC | 2-1 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | West Bromwich Albion | Brighton and Hove Albion | 1-2a.e.t | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Newcastle United | Cambridge United | 0-1 | 5 - 7 points |
| 1/8/22 9:00 AM | 1/8/22 9:00 AM | Wigan Athletic | Blackburn Rovers | 3-2 | 5 - 7 points |
| 1/8/22 11:30 AM | 1/8/22 11:30 AM | Swansea City | Southampton FC | 2-3a.e.t | 5 - 7 points |
| 1/8/22 11:30 AM | 1/8/22 11:30 AM | Hull City A.F.C. | Everton FC | 2-3a.e.t | 5 - 7 points |
| 1/8/22 11:30 AM | 1/8/22 11:30 AM | Birmingham City | Plymouth Argyle | 0-1a.e.t | 5 - 7 points |
| 1/8/22 11:30 AM | 1/8/22 11:30 AM | Chelsea FC | FC Chesterfield | 5-1 | 5 - 7 points |
| 1/8/22 11:45 AM | 1/8/22 11:45 AM | Yeovil Town | AFC Bournemouth | 1-3 | 5 - 7 points |
| 1/9/22 6:30 AM | 1/9/22 6:30 AM | Luton Town | Harrogate Town FC | 4-0 | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | Tottenham Hotspur | FC Morecambe | 3-1 | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | Stoke City | Leyton Orient | 2-0 | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | Liverpool FC | Shrewsbury Town | 4-1 | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | Cardiff City | Preston North End | 2-1a.e.t | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | Charlton Athletic | Norwich City | 0-1 | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | Wolverhampton Wanderers | Sheffield United | 3-0 | 5 - 7 points |
| 1/9/22 8:00 AM | 1/9/22 8:00 AM | West Ham United | Leeds United | 2-0 | 5 - 7 points |
| 1/9/22 11:10 AM | 1/9/22 11:10 AM | Nottingham Forest | Arsenal FC | 1-0 | 5 - 7 points |
| 1/10/22 1:55 PM | 1/10/22 1:55 PM | Manchester United | Aston Villa | 1-0 | 5 - 7 points |