Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/1/21 1:45 PM | 10/1/21 1:45 PM | Cagliari Calcio | FC Venice | 1-1 | 2 - 5 points |
| 10/2/21 8:05 AM | 10/2/21 8:05 AM | US Salernitana | Genua CFC | 1-0 | 2 - 5 points |
| 10/2/21 11:00 AM | 10/2/21 11:00 AM | FC Turin | Juventus Turin | 0-1 | 2 - 5 points |
| 10/2/21 1:45 PM | 10/2/21 1:45 PM | Sassuolo Calcio | Inter Milan | 1-2 | 2 - 5 points |
| 10/3/21 5:30 AM | 10/3/21 5:30 AM | FC Bologna | Lazio Rom | 3-0 | 2 - 5 points |
| 10/3/21 8:00 AM | 10/3/21 8:00 AM | Sampdoria Genua | Udinese Calcio | 3-3 | 2 - 5 points |
| 10/3/21 8:00 AM | 10/3/21 8:00 AM | Hellas Verona | Spezia Calcio | 4-0 | 2 - 5 points |
| 10/3/21 11:00 AM | 10/3/21 11:00 AM | AS Roma | FC Empoli | 2-0 | 2 - 5 points |
| 10/3/21 11:05 AM | 10/3/21 11:05 AM | Fiorentina | SSC Napoli | 1-2 | 2 - 5 points |
| 10/3/21 1:45 PM | 10/3/21 1:45 PM | Atalanta Bergamo | AC Milan | 2-3 | 2 - 5 points |