Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/21/21 11:30 AM | 9/21/21 11:30 AM | FC Bologna | Genua CFC | 2-2 | 2 - 5 points |
| 9/21/21 1:45 PM | 9/21/21 1:45 PM | Atalanta Bergamo | Sassuolo Calcio | 2-1 | 2 - 5 points |
| 9/21/21 1:45 PM | 9/21/21 1:45 PM | Fiorentina | Inter Milan | 1-3 | 2 - 5 points |
| 9/22/21 11:30 AM | 9/22/21 11:30 AM | Spezia Calcio | Juventus Turin | 2-3 | 2 - 5 points |
| 9/22/21 11:30 AM | 9/22/21 11:30 AM | US Salernitana | Hellas Verona | 2-2 | 2 - 5 points |
| 9/22/21 1:45 PM | 9/22/21 1:45 PM | Cagliari Calcio | FC Empoli | 0-2 | 2 - 5 points |
| 9/22/21 1:45 PM | 9/22/21 1:45 PM | AC Milan | FC Venice | 2-0 | 2 - 5 points |
| 9/23/21 11:30 AM | 9/23/21 11:30 AM | Sampdoria Genua | SSC Napoli | 0-4 | 2 - 5 points |
| 9/23/21 11:30 AM | 9/23/21 11:30 AM | FC Turin | Lazio Rom | 1-1 | 2 - 5 points |
| 9/23/21 1:45 PM | 9/23/21 1:45 PM | AS Roma | Udinese Calcio | 1-0 | 2 - 5 points |