Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 9/11/21 8:00 AM | 9/11/21 8:00 AM | FC Empoli | FC Venice | 1-2 | 2 - 5 points |
| 9/11/21 11:00 AM | 9/11/21 11:00 AM | SSC Napoli | Juventus Turin | 2-1 | 2 - 5 points |
| 9/11/21 1:45 PM | 9/11/21 1:45 PM | Atalanta Bergamo | Fiorentina | 1-2 | 2 - 5 points |
| 9/12/21 5:30 AM | 9/12/21 5:30 AM | Sampdoria Genua | Inter Milan | 2-2 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | FC Turin | US Salernitana | 4-0 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | Cagliari Calcio | Genua CFC | 2-3 | 2 - 5 points |
| 9/12/21 8:00 AM | 9/12/21 8:00 AM | Spezia Calcio | Udinese Calcio | 0-1 | 2 - 5 points |
| 9/12/21 11:00 AM | 9/12/21 11:00 AM | AC Milan | Lazio Rom | 2-0 | 2 - 5 points |
| 9/12/21 1:45 PM | 9/12/21 1:45 PM | AS Roma | Sassuolo Calcio | 2-1 | 2 - 5 points |
| 9/13/21 1:45 PM | 9/13/21 1:45 PM | FC Bologna | Hellas Verona | 1-0 | 2 - 5 points |